What is Viagra (Sildenafil Citrate)?
“Viagra” is sold in the form of pills by 25, 50 and 100 mg which contain, correspondingly, 25, 50 and 100 mg of Sildenafil citrate.
In contrast to other methods of erectile dysfunction treatment such as injections into penis and other medical procedures, Viagra is a simple, convenient and easily used medication. When using Viagra you just take one pill before a sexual contact.
Mechanism of action of Viagra is simple: the medication increases the amount of the blood coming to penis. This helps man to evoke a natural erection. Viagra acts only when a man feels natural sexual stimulation. When coitus is finished – a penis returns to its natural slackness. In other words, Viagra has an effect only on natural mechanisms of erection rise and that is its incontrovertible novelty and secret of a huge popularity.
Discovery of Viagra has become, obviously, the third greatest “fortuitous” discovery in the medicine – after the discovery of X-ray beams and penicillin. These discoveries were awarded with the Nobel Prize. In autumn 1998 the same Award was given to the researchers who had discovered in addition the characteristics of medication Viagra.
The history of Viagra began in the Great Britain, 1992 – Pfizer’s Sandwich in the course of pharmacological studies of “Pfizer” company. The researchers carried out clinical trials of a new medicine substance – Sildenafil citrate which had been developed as a preparation to treat a number of cardiac diseases.
The scientists believed that Sildenafil citrate would stimulate increase of blood inflow to cardiac muscle and decrease of arteriotony. However it was noted that Sildenafil citrate did not influence much neither circulation of the blood in the cardiac muscle (myocardium) nor arteriotony. It was also found out that a lot of male sex patients who took part in studies, refused to return Sildenafil pills despite of the end of testing. The reason was the same for all patients- all of them noticed sudden improvement of erection quality. Thus, despite of the minimal influence of the new medication on circulation of the blood in the myocardium, Sildenafil provoked a significant blood inflow to penis.
The researchers of the pharmacological company “Pfizer” regarded this sudden property of Sildenafil citrate attentively and managed to find out a powerful preparation for erectile dysfunction treatment in this medication. The new preparation was called Viagra – the name was invented as a result of words junction “Vigor” (power, energy, strength) and Niagara – the most powerful waterfall in the North America.
Since 1993 long clinical trials necessary for confirmation of Viagra properties took place. In a result of these trials a high effectiveness of Viagra for impotence treatment and safety of this medication had been confirmed. And as an expected final – on 27th of March 1998 FDA approved the use of Viagra. The effect of Viagra was estimated by more than 3000 men in the age from 19 to 87 during the studies of erectile dysfunction which were carried out in all countries of the world. The duration of erection disorders formed on average 5 years (from 6 months to 26 years) and erectile dysfunctions were of organic, psychogenic and mixed organic and psychogenic origins.
The results of these investigations show that Viagra medication is effective for erectile function recovery as well as for increase of number of successful coituses in the majority of patients including a number of diabetics, people having damaged spinal cord and other attendant clinical states as well as in patients who take various medications simultaneously.
According to data of many clinical investigations and trials of the medications on volunteers having different types of erectile dysfunction, Sildenafil citrate is extremely effective. However it is necessary to mention some nuances.
Unfortunately, there is no such medication in the world which could treat all the diseases or, as for our very case, all the types of erectile dysfunction. Viagra is capable to help in a huge number of cases however, unfortunately, not to all the patients. Viagra is very effective for patients with atherosclerosis, damage of nerves which go to vessels of a penis, diabetes mellitus.
But not excellent results mat be observed in patients who have pathologic venous drainage. In every case of the treatment of erectile dysfunction which has just been mentioned above only the doctor may know exactly the details. Only the doctor may prescribe the correct scheme of treatment and choose the best medication.







