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Drugs currently on the market but used for other purposes helped plump mice shed pounds by upping their response to the appetite-suppressing hormone leptin, according to a new study. Researchers say the findings offer new hope in the search for weight-loss meds that exploit the hunger-dampening hormone, first discovered some 13 years ago.
“Leptin is a [...]
When we say, “all time,” we mean it. The news talks about obesity like it’s a recent epidemic, but the truth is that fat people have existed throughout recorded history. Without modern inventions, people in earlier times had to work 10 times harder to get fat, but the extraordinary men and women of those eras [...]
Appetite is controlled by many factors (Figure 3.1). Processes in the body tell people when they are hungry and when they are satiated (full). Neurotransmitters (chemical messengers in the brain) such as norepinephrine, serotonin, and dopamine tell the brain that the stomach feels full (Figure 3.2). Drugs that increase the levels of these neurotransmitters cause [...]
After food is eaten, it is digested in the stomach. The digested nutrients from food are absorbed, mainly in the intestines, into the bloodstream and are used as fuel for the body.When people eat more food than they need, the body stores the extra nutrients as fat, which accounts for weight gain.
Some diet drugs are [...]
Calories consumed in food are used by the body as fuel. The body’s use of calories as its source of energy is called thermogenesis. Literally, thermogenesis means “the production of heat” because when people burn calories, heat is produced. The body needs a constant supply of fuel to maintain normal functions that people don’t [...]
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